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	Provedor de dados BJPS (2) Autor Jose,Jobin (2) Fernandes,Amanda Velinna (1) Gopalan,Kavya (1) Kumar,Lalit (1) Pydi,Chinna Raja (1) Verma,Ruchi (1) Mais... Palavra-chave Amphotericin B (1) Design of experiment (1) Fluconazole (1) Full factorial design (1) Fungal infections (1) Lecithin (1) NLCs (1) Nanostructured lipid carriers (1) Organogel (1) Pluronic F127 (1) Span 60 (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2020 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Design, preparation and in vitro characterizations of fluconazole loaded nanostructured lipid carriers BJPS Fernandes,Amanda Velinna; Pydi,Chinna Raja; Verma,Ruchi; Jose,Jobin; Kumar,Lalit. Present study was aimed to prepare and characterize fluconazole loaded nanostructured lipid carriers (FLZ-NLCs) for the treatment of fungal infections. Fungal infections are tremendously widespread and are the often faced dermatological condition worldwide. FLZ-NLCs was prepared by ultrasonication emulsion technique using stearic acid (SA) as solid lipid, castor oil as liquid lipid and tween 20 as a surfactant. The mean diameter of optimized FLZ-NLCs were found to be 359.15 ± 9.83 nm. The drug content and entrapment efficiency of NLCs was found to be 102.97 ± 7.45% and 87 ± 0.59%, respectively. In vitro drug release studies of FLZ-NLCs showed 37.34 ± 2.08% drug release over a period of 72 h. The above studies confirmed the prepared FLZ-NLCs may be useful... Tipo: Info:eu-repo/semantics/article Palavras-chave: Fluconazole; NLCs; Nanostructured lipid carriers; Fungal infections; Full factorial design; Design of experiment. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100524 Development of amphotericin b Based organogels against mucocutaneous fungal infections BJPS Gopalan,Kavya; Jose,Jobin. Amphotericin B is a broad spectrum antifungal agent used to treat fungal infections. Organogel is a semisolid preparation in which the apolar phase gets immobilized within spaces of the three-dimensional structure. The current study aimed at the formulation and comparative evaluation of sorbitan monostearate organogels and pluronic lecithin organogels (PLO). Different compositions of span 60 based organogels were prepared by varying the concentrations of the span 60 and PLO gels were prepared by varying the concentration of Pluronic F 127. The developed organogels were subjected to various characteristics such as pH, viscosity, spreadability, extrudability, and drug release studies. The optimized formulations were evaluated against Candida albicans and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Amphotericin B; Organogel; Span 60; Pluronic F127; Lecithin. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100563 Registros recuperados: 2 Primeira ... 1 ... Última

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